Hydrochloric acid in the correction of metabolic alkalosis.

Correction of metabolic alkalosis by the kidney after isomertric expansion of extracellular fluid.

Metabolic alkalosis was induced in dogs by administering ethacrynic acid and sustained by feeding a chloride-deficient diet. At the height of the alkalosis extracellular fluid was expanded "isometrically," i.e., with an infusion that duplicated plasma sodium, chloride, and bicarbonate concentrations. Correction of metabolic alkalosis promptly followed such expansion and was attributed to the se...

Metabolic alkalosis treated with intravenous hydrochloric acid.

The rational use of i.v. hydrochloric acid in the treatment of metabolic alkalosis.

A method for the assessment and management of factors both causing and maintaining a primary metabolic alkalosis is presented. During a 2-year period 65 patients with metabolic alkalosis were treated with saline and potassium chloride infusions. In four patients the alkalosis was refractory and required additional therapy. An infusion of hydrochloric acid 0.12-0.24 mol/litre through a central v...

Dermal gangrene. A rare complication of warfarin therapy.

HAGGIE, S.J., FERMONT, D.C. & WYLLIE, J.H. (1976) Treatment of duodenal ulcer with cimetidine. Lancet, i, 983. HARKEN, A.H., GABEL, R.A., FENEL, V. & MOORE, F.D. (1975). Hydrochloric acid in the correction of metabolic alkalosis. Archives of Surgery, 110, 819. HERTZ, P. & RICHARDSON, J.A. (1972) Arginine-induced hyperkalemia in renal failure patients. Archives of Internal Medicine, 130, 778. KA...

The use of dilute hydrochloric acid and cimetidine to reverse severe metabolic alkalosis.

Two cases of severe metabolic alkalosis associated with gastric hypersecretion were successfully treated with dilute hydrochloric acid and a histamine H2-receptor antagonist given by intravenous infusion. This combined therapy with electrolyte replacement and suppression of gastric secretion is valuable in the control of this serious metabolic abnormality when conventional treatment is unsucces...